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Condition
Select the primary diagnosis
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Patient profile
Demographics and baseline characteristics
Relevant for ustekinumab, some biologics
Used to flag scoring limitations in skin of color
Type I
Always burns
Type II
Usually burns
Type III
Sometimes burns
Type IV
Rarely burns
Type V
Very rarely burns
Type VI
Never burns
Skin of color — scoring note
PASI and EASI scores may underestimate disease severity in Fitzpatrick IV–VI. Erythema appears violaceous rather than red. Consider itch burden, sleep impact, and QoL metrics alongside visual scoring.
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Disease characteristics
Current disease burden and distribution
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Comorbidities
Select all that apply — these directly affect biologic choice
Psoriatic arthritis
Favors IL-17 / IL-23 agents
Inflammatory bowel disease
Critical — affects IL-17 eligibility
Cardiovascular disease
Favors IL-23 inhibitors
Allergic asthma
Favors dupilumab (if AD)
Recurrent serious infections
Caution with all biologics
Demyelinating disease
Contraindicates TNF inhibitors
Diabetes
Consider monitoring requirements
Obesity (BMI >30)
Affects ustekinumab efficacy
Pregnancy / planning pregnancy
Significantly affects biologic choice
Prior or active malignancy
Caution with some agents
Hepatitis B (active or prior)
Antiviral prophylaxis required
TB exposure / latent TB
Must be treated before TNF inhibitors
Pregnancy status

Note: Certolizumab (Cimzia) is the preferred TNF inhibitor in pregnancy — does not cross placenta. For AD, dupilumab has the most reassuring registry data.

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Treatment history
Prior and current treatments
Add each biologic tried — drug and reason for stopping
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Practical factors
Access, preference, and adherence considerations
Oral options exist for some conditions (JAK inhibitors, TYK2 inhibitor)
Applicable options
Updates live as you complete the form
Complete the form above — applicable biologics will appear here as you make selections.
Complete the form above to generate a personalized biologic recommendation with contraindication alerts and skin-of-color specific guidance.

For educational and training purposes only. Not a substitute for clinical judgment or institutional prescribing guidelines.